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. Author manuscript; available in PMC: 2018 Feb 5.
Published in final edited form as: Mol Genet Metab. 2017 Jun 3;122(1-2):92–99. doi: 10.1016/j.ymgme.2017.06.001

Fig. 4.

Fig. 4

Treatment algorithm for monitoring idursulfase ERT efficacy. Abbreviations: DMB = direct 1,9-dimethylmethylene blue. ERT = enzyme replacement therapy. GAG = glycosaminoglycans. NICIT = non-immunosuppressive and non-cytotoxic immune tolerance.