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. 2017 Dec 11;293(5):1820–1834. doi: 10.1074/jbc.M117.814152

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Figure 4. — Enrichment profiles of residues in various regions of Vα and Vβ of T1 TCR under different sorting conditions. A, average enrichment scores (log₂ ratio) for all substitutions in various regions of Vα and Vβ when sorted with different ligands. B, percentage substitutions in monomer-sorted T1-SCL that were enriched above a set cutoff (i.e. 8-, 11-, or 16-fold (corresponding to enrichment scores of 2³, 2^3.5, or 2⁴) over remaining possible substitutions in CDR or interface or surface framework regions of Vα and Vβ. Tetramer/Monomer, tetrameric/monomeric MART-1·HLA-A2.