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Interaction between FBXO31 and CDH1 or CDC20 is perturbed following DNA damage. (A) Coimmunoprecipitation monitoring the interaction between endogenous FBXO31 and CDH1 or CDC20 in asynchronous HEK293T cells treated with or without IR. (B) Coimmunoprecipitation monitoring the interaction between endogenous FBXO31 and CDH1 or CDC20 in HEK293T cells expressing a NS or ATM shRNA, with or without IR. (C) Model for regulation of FBXO31 by APC/C.
