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. 2018 Jan 16;115(5):E925–E933. doi: 10.1073/pnas.1718283115

Table 2.

Summary of kinetic analysis data for six biomarkers using SPR

Analyte Association rate constant ka, M−1 s−1 Dissociation rate constant kd, s−1 Equilibrium dissociation constant Kd, M
GDNF 1.4 E+07 <1.0 E−05 <7.1 E−13
IL-6 2.3 E+06 <1.0 E−05 <4.3 E−12
VEGF 1.6 E+07 5.6 E−05 3.6 E−12
IGF-II 4.9 E+05 2.5 E−05 5.1 E−11
MIF 1.1 E+06 9.4 E−05 8.3 E−11
TNF-α 5.7 E+05 1.6 E−04 2.8 E−10