Table 3.

Global network measures, compared for each group. All network measures were calculated using a threshold of 0.0005 (>five total tracts between regions of interest (ROIs)), and using permutation testing to assess significance

Measure	MCI-highEF: mean ± SD	MCI-lowEF: mean ± SD	t: MCI-highEF – MCI-lowEF	Permutation t-statistic: mean ± SD	p-value
Size	567.47 ± 122.2	541.38 ± 42.9	26.09	1.70 ± 5.5	<0.001
Density	0.134 ± 0.029	0.129 ± 0.010	0.005	−.0016 ± 0.0013	<0.001
Assortativity	0.0508 ± 0.064	0.0586 ± 0.054	−0.0079	−0.004 ± 0.0013	0.3835
Global efficiency	0.4881 ± 0.058	0.4858 ± 0.016	0.0023	−2.9e-4 ± 0.0015	0.09
Clustering coefficient	0.0109 ± 1.9e-4	0.0069 ± 1.7e-4	0.0039	−1.0e-4 ± 1.5e-4	<0.001

The t-statistic (MCI-highEF (mild cognitive impairment with high executive abilities) – MCI-lowEF (cognitive impairment with low executive abilities) is reflected, and the mean of the 10,000 randomly generated t-statistics, with the standard deviation of the population also reflected. The p-value reflects where on the randomly generated t-statistic distribution the measured t-statistic lies

MCI-highEF Individuals with mild cognitive impairment with high executive abilities, MCI-lowEF Individuals with cognitive impairment with low executive abilities, SD standard deviation