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. Author manuscript; available in PMC: 2018 Dec 4.
Published in final edited form as: Neuroscience. 2017 Sep 23;365:23–32. doi: 10.1016/j.neuroscience.2017.09.034

Figure 6. BK depolarizes cardiac-projecting nucleus ambiguus neurons.

Figure 6

A, Characteristic changes in membrane potential elicited by BK (20 nM) alone or after B1 (R715) or B2 (HOE140) receptor antagonist pretreatment in rhodamine-labeled cardiac vagal nAmb neurons. B, Response quantifications reveal concentration-dependent depolarizing effect of BK (2–200 nM) on the resting membrane potential of cardiac preganglionic neurons;; n = 6 neurons for each condition. *P < 0.05 when compared with resting membrane potential and within the group; NS, not significant and #P < 0.05 when compared with the depolarizing effect of BK (20 nM).