TABLE 3.
Cox Proportional Hazard Model of Overall Survival
Covariate | Level | Hazard Ratio | P Value |
---|---|---|---|
Extent of lung resection | Segmental resection | 1.33 (1.11–1.60) | 0.002 |
Wedge resection | 1.54 (1.42–1.67) | <0.001 | |
Lobectomy | — | — | |
Facility type | Academic/research program (Includes NCI) | 0.86 (0.75–0.99) | 0.041 |
Comprehensive community cancer program | 0.92 (0.80–1.05) | 0.194 | |
Community cancer program/other | — | — | |
Sex | Male | 1.24 (1.15–1.33) | <0.001 |
Female | — | — | |
Patient age | 1.03 (1.02–1.03) | <0.001 | |
Insurance | Not insured | 0.83 (0.56–1.23) | 0.356 |
Private insurance | 0.83 (0.76–0.92) | <0.001 | |
Govenment insurance | — | — | |
Income | <$30,000 | 1.33 (1.18–1.50) | <0.001 |
$30,000–$34,999 | 1.30 (1.17–1.44) | <0.001 | |
$35,000–$45,999 | 1.14 (1.04–1.25) | 0.007 | |
$46,000+ | — | — | |
Charlson/Deyo score | 2+ | 1.52 (1.36–1.69) | <0.001 |
1 | 1.17 (1.08–1.27) | <0.001 | |
0 | — | — | |
Histology | Unknown histology | 1.16 (0.98–1.36) | 0.080 |
Squamous cell carcinomas | 1.06 (0.96–1.16) | 0.246 | |
Other tumorsa | 0.78 (0.59–1.02) | 0.074 | |
Large-cell carcinomas | 1.09 (0.90–1.33) | 0.366 | |
Adenosquamous carcinomas | 1.18 (0.93–1.50) | 0.171 | |
Adenocarcinomas | — | — | |
Grade | Unknown, high-grade dysplasia | 1.33 (1.12–1.58) | <0.001 |
3–4 | 1.57 (1.38–1.79) | <0.001 | |
2 | 1.43 (1.27–1.62) | <0.001 | |
1 | — | — | |
Size of tumor (cm) | 1.21 (1.10–1.34) | <0.001 |
Number of observations in the original data set = 28,241. Number of observations used = 6438. Tumor location was included in the multivariable model but not shown here.
Including but not restricted to, spindle cell carcinoma, mucoepidermoid malignancies, neuroendocrine, and mixed malignant tumors.