TABLE 4.
Multivariate Association with Long-Term Mortality—Interaction with Facility Type, Tumor Size, and Number of Lymph Nodes Examined
| Covariates | Level | Hazard Ratio | HR P Value | Type 3 P Valuea |
|---|---|---|---|---|
| Stratified comparisons by facility type | — | — | 0.035 | |
| Noncomprehensive community cancer program/other | Wedge resection (186) vs. lobectomy (440) | 1.34 (1.02–1.76) | 0.032 | — |
| Segmental resection (27) vs. lobectomy (440) | 2.11 (1.24–3.60) | 0.006 | ||
| Comprehensive community cancer program | Wedge resection (987) vs. lobectomy (2639) | 1.47 (1.32–1.64) | <0.001 | — |
| Segmental resection (129) vs. lobectomy (2639) | 1.09 (0.82–1.44) | 0.561 | ||
| Academic/research program | Wedge resection (718) vs. lobectomy (1778) | 1.73 (1.51–1.98) | <0.001 | — |
| Segmental resection (130) vs. Lobectomy (1778) | 1.51 (1.16–1.96) | 0.002 | ||
| Stratified comparisons by tumor size | 0.203 | |||
| 0–1 cm | Wedge resection (439) vs. lobectomy (722) | 1.77 (1.45–2.16) | <0.001 | — |
| Segmental resection (51) vs. lobectomy (722) | 1.24 (0.74–2.06) | 0.414 | ||
| 1–2 cm | Wedge resection (1452) vs. lobectomy (4135) | 1.47 (1.35–1.61) | <0.001 | — |
| Segmental resection (235) vs. lobectomy (4135) | 1.32 (1.09–1.60) | 0.004 | ||
| Stratified comparisons by regional LN examined | 0.655 | |||
| 0–7 | Wedge resection (1739) vs. lobectomy (2881) | 1.50 (1.37–1.65) | <0.001 | — |
| Segmental resection (246) vs. lobectomy (2881) | 1.27 (1.04–1.55) | 0.020 | ||
| 8+ | Wedge resection (152) vs. lobectomy (1976) | 1.56 (1.21–2.01) | <0.001 | — |
| Segmental resection (40) vs. lobectomy (1976) | 1.58 (1.01–2.48) | 0.044 |
Sample size for each subgroup listed in parenthesis.
a
Type 3 P value indicates the significance for the interaction term in the fitted model. LN, lymph nodes.