Figure 1. Risk of oral clefts in the exposed and reference groups.

Prevalence of oral clefts at birth (dots) and 95% confident intervals (lines) in infants after maternal exposure to topiramate and in the unexposed and lamotrigine-exposed reference groups. The topiramate-exposed group was further divided according to indication and, within monotherapy, by dose. Medicaid Analytic eXtract, 2000 to 2010.