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. 2017 Dec 20;8(1):2045893217752328. doi: 10.1177/2045893217752328

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© The Author(s) 2018

Creative Commons CC-BY: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 5. — Macitentan treatment induces changes in inflammatory plasma cytokines in HFD-fed ApoE^−/− mice. Bar charts show the plasma concentration of (a) IL-6, (b) leptin, (c) IL-10, (d) IL-1β, (e) MCP-1, (f) TNF-α, (g) HGF, (h) insulin, (i) IP-10, (j) SDF-1, and (k) CRP. Bar graphs represent mean ± SEM, n = 4–9 with individual animals represented by dots. *P < 0.05. Statistical differences were assessed by Mann–Whitney U test.