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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: IEEE Trans Biomed Eng. 2017 Oct 16;65(2):273–281. doi: 10.1109/TBME.2017.2763460

Table I.

Summary of signal processing techniques

Method Equation Variable Definition Description References
Dominant Frequency
(DF)
DF=argmaxf(X(f))
X(f); spectrum of the voltage intensity time series Calculates the peak frequency in the signal spectrum (0–30 Hz) of the voltage intensity time series. 11–14
Multiscale Frequency
(MSF)
MSF=ρo[i=1N1qi]1i=1N=12i+0.5qi+1
ρ: local MSF estimate
qi: output of the ith log-Gabor filter
ρo: center frequency of the first log-Gabor filter
Calculates the instantaneous frequency using the signal spectrum (0–30 Hz) of the voltage intensity time series 24
Shannon Entropy
(SE)
SE=i=0N1pilog2pi
N: number of amplitude bins
ρ: probability of any sample falling within a particular amplitude bin
Quantifies the uncertainty in the voltage intensity distribution 20, 23
Kurtosis
(Kt)
Kt=E{(x(t)E{x(t)}σx)4}
E: expected value
x(t): voltage intensity time series
σx: variance of the voltage intensity time serie
Quantifies the ‘peakedness’ of the voltage intensity distribution 25
Multiscale Entropy
(MSE)
MSE=log(AB)
A: number of matched vector pairs of length m+1 from the moving average time series
B: number of matched vector pairs of length m from the moving average time series
Calculates the moving average of the voltage intensity time series and quantifies the regularity and repetitiveness of the data 26