Table 1.
Characteristics of Study Participants at Baseline, According to Study Site and Phase.*
| Characteristic | Freetown Site | Lungi Site | Total | |
|---|---|---|---|---|
| Phase 1 (N = 100) | Phase 2 (N = 60) | Phase 2 (N = 60) | Phases 1 and 2 (N = 220) | |
| Recruitment period | May 27, 2015–July 7, 2015 | Nov. 11, 2015–Feb. 17, 2016 | Feb. 3, 2016–May 12, 2016 | May 27, 2015–May 12, 2016 |
|
| ||||
| Age | ||||
|
| ||||
| Mean — yr | 29.7±8.4 | 31.3±8.3 | 34.8±11.5 | 31.5±9.5 |
|
| ||||
| Median (interquartile range) — yr | 27 (24–34) | 30 (25–36) | 34 (26–43) | 29 (25–36) |
|
| ||||
| Distribution — no./total no. (%) | ||||
|
| ||||
| ≤25 yr | 36/99 (36) | 18/60 (30) | 13/60 (22) | 67/219 (31) |
|
| ||||
| 26–35 yr | 44/99 (44) | 25/60 (42) | 22/60 (37) | 91/219 (42) |
|
| ||||
| >35 yr | 19/99 (19) | 17/60 (28) | 25/60 (42) | 61/219 (28) |
|
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| Highest level of education — no. (%)† | ||||
|
| ||||
| No education | 14 (14) | 10 (17) | 19 (32) | 43 (20) |
|
| ||||
| Primary education | 49 (49) | 13 (22) | 8 (13) | 70 (32) |
|
| ||||
| Secondary education | 37 (37) | 37 (62) | 33 (55) | 107 (49) |
|
| ||||
| Marital status — no. (%) | ||||
|
| ||||
| Married or in a long-term relationship | 51 (51) | 31 (52) | 40 (67) | 122 (55) |
|
| ||||
| Single, divorced, widowed, or separated | 49 (49) | 29 (48) | 20 (33) | 98 (45) |
|
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| Current household size, including self — no./total no. (%) | ||||
|
| ||||
| ≤4 persons | 32/100 (32) | 17/57 (30) | 7/59 (12) | 56/216 (26) |
|
| ||||
| 5–8 persons | 30/100 (30) | 35/57 (61) | 8/59 (14) | 73/216 (34) |
|
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| 9–12 persons | 27/100 (27) | 4/57 (7) | 12/59 (20) | 43/216 (20) |
|
| ||||
| >12 persons | 11/100 (11) | 1/57 (2) | 32/59 (54) | 44/216 (20) |
|
| ||||
| No. of household members with EVD, excluding self — no. (%) | ||||
|
| ||||
| 0 | 36 (36) | 16 (27) | 6 (10) | 58 (26) |
|
| ||||
| 1 or 2 | 34 (34) | 16 (27) | 11 (18) | 61 (28) |
|
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| 3 or 4 | 15 (15) | 13 (22) | 14 (23) | 42 (19) |
|
| ||||
| ≥5 | 15 (15) | 15 (25) | 29 (48) | 59 (27) |
|
| ||||
| Duration between ETU discharge and semen-specimen collection | ||||
|
| ||||
| Mean — mo | 5.9±1.9 | 11.5±3.2 | 15.6±2.9 | 10.0±4.9 |
|
| ||||
| Median (interquartile range) — mo | 6.2 (4.5–7.1) | 11.3 (9.0–14.0) | 15.5 (13.7–17.5) | 8.6 (6.2–14.2) |
|
| ||||
| Range — mo | 1.3–11.2 | 4.1–19.3 | 8.5–22.3 | 1.3–22.3 |
|
| ||||
| No semen specimen — no. | 2 | 5 | 3 | 10 |
|
| ||||
| Result of Ebola RT-PCR semen testing at baseline — no./total no. (%) | ||||
|
| ||||
| Positive | 46/98 (47) | 8/55 (15) | 3/57 (5) | 57/210 (27) |
|
| ||||
| Indeterminate‡ | 13/98 (13) | 0/55 | 0/57 | 13/210 (6) |
|
| ||||
| Negative | 39/98 (40) | 47/55 (85) | 54/57 (95) | 140/210 (67) |
*
Plus–minus values are means ±SD. The Freetown site is in an urban area, and the Lungi site in a semiurban area. Percentages may not total 100 because of rounding. ETU denotes Ebola treatment unit, EVD Ebola virus disease, and RT-PCR reverse transcriptase–polymerase chain reaction.
†
Primary education was defined as 1 to 8 years of school, and secondary education as more than 8 years of school.
‡
An indeterminate result indicates that one of the gene targets was detected and one was not detected; this finding applies only to the assay from the Centers for Disease Control and Prevention that was used during phase 1.