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Proposed uridylylation pathway for U2-tfs that are diverted from the degradation pathway for U1-tfs. U1-tfs and U2-tfs are formed from a small population of U1 and U2 transcripts having all cis-elements or lacking the 3’ box, respectively. Whereas U1-tfs are delivered to P-bodies for degradation, U2-tfs are uridylylated by a TUT other than TUT7 to form U2-tfs-polyU, which is stabilized by SmB/B’ possibly by forming an Sm ring, or is degraded in a manner that is dependent on TUT7.
