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. Author manuscript; available in PMC: 2018 Jul 1.

Published in final edited form as: Breast Cancer Res Treat. 2017 Apr 26;164(2):371–378. doi: 10.1007/s10549-017-4265-x

Table 3.

Change from baseline at 6 months

	Metformin	Placebo	Total
	Change Median (IQR)	Change Median (IQR)	Change Median (IQR)	P
Vitamin B12	n= 234	n = 253	n= 487	<.001
Vitamin B12	−51 (6, −182)	+0 (−61, +65)	−26 (−107, 45)	<.001
Hemoglobin	n=232	n=252	n=484	0.35
Hemoglobin	+ 1 (−4, 5.5)	+2 (−3, 8)	+1.5 (−3.5, 6.5)	0.35

IQR = interquartile range, N= number of patients