Figure 5.

Isolating the effects of ${\lambda }_{1_{\mathit{HGF}}}$ and ${\lambda }_{2_{\mathit{HGF}}}$ in Equations (18), (20), and (21) on stem cell distributions and concentrations of c-Met and c-Met inhibitors. Stem cell distribution is shown for T = 150 and ( ${\lambda }_{1_{\mathit{HGF}}}$, ${\lambda }_{2_{\mathit{HGF}}}$) as indicated. The bottom right-hand corner of each simulation shows the maximum concentration of c-Met and c-Met inhibitor that is reached (the short-hand M(X) = max(X) is used). Note that δ₁ and δ₂ in Equations (5) and (6) are set to 0 to control for the HGF-induced effect on cell scatter.