γ |
Global adhesion |
−0.1 |
(*) |
ε |
Diffuse interface thickness |
0.05 |
(*) |
Mb |
Mobility |
10.0 |
(*) |
δ1
|
Strength of M effect on F(ϕT), measure of cell scatter |
0.02 |
Section 3.2 |
δ2
|
Strength of M effect on Ẽ, the energy scale |
0.02 |
Section 3.2 |
κ |
Pressure-dependent cell motility |
1.0 |
(*) |
λMTC |
TC mitosis rate |
0.1 |
(*) |
λATC |
TC death rate |
0.1 |
(*) |
λL |
DC lysis rate |
1.0 |
(*) |
Pmin |
Min. CSC self-renewal rate |
0.2 |
(*) |
Pmax |
Max. CSC self-renewal rate |
1.0 |
(*) |
ξ0
|
Strength of M action on P0
|
1.0 |
(*) |
ψ0
|
Strength of TGFβ action on P0
|
1.0 |
Section 3.1 |
|
Min. CSC mitosis rate |
0.5 |
Estimated, (Frank, 2007, Chapter 12) |
|
Max. CSC mitosis rate |
1.5 |
Estimated, (Frank, 2007, Chapter 12) |
ξ1
|
Strength of M action on λMSC
|
0.5 |
Estimated by simulation |
ψ1 |
Strength of TGFβ action on λMSC
|
0.5 |
(**) |