Table 2.

Nondimensionalized chemical species parameters (Sections 2.5, 2.6).

Parameter	Description	Value	Reference
νUOTC	Oxygen uptake rate by TCs	1.0	(*)
νPO	Oxygen transfer rate	0.5	(*)
νUTGFβ	TGFβ uptake rate by CSCs	0.05	(*)
νTGFβ	TGFβ decay rate	0.0	(*)
νPTGFβ	TGFβ production rate by TCs	0.1	(*)
DM	Diffusion of M effectors	1.0	(*)
DMI	Diffusion of MI effectors	25.0	(*)
ν0	Strength of HGF-independent M activation	1.0	(*)
${\lambda }_{1,2_{\mathit{HGF}}}$	Strength of HGF-induced M activation	0.5	Section 3.2
νDM	M decay rate	1.0	(*)
ηM	Background M production rate	0.2	(*)
νDMI	MI Decay rate	1.0	(*)
R	Reaction rate	50.0	(*)
νPHGF	Strength of SGF on HGF activation	{5,10,15}	Sections 3.1, S3
νDHGF	HGF decay rate	1.0	(**)
DHGF	HGF diffusion rate	0.1	(**)
νSGFS	SGF production rate by CSCs	{5,10,15}	Section 3.1, S3
νSGFT	SGF production rate by TCs	{5,10,15}	Section 3.1, S3
νDSGF	SGF decay rate	1.0	(**)
DSGF	SGF diffusion rate	1.0	(**)