Table 2.
BMI group | Placebo | Nasal Mometasone | P value |
---|---|---|---|
Change from V2 to V5* | Change from V2 to V5* | ||
FEV1 (% predicted) | |||
< 25 | 0.82 (−1.22, 2.86) | 1.69 (−1.04, 4.41) | 0.61 |
25–29.9 | 1.68 (−2.71, 6.08) | −3.18 (−7.57, 1.22) | 0.12 |
> 30 | −0.06 (−3.43, 3.30) | −1.99 (−5.11, 1.12) | 0.41 |
FVC (% predicted) | |||
< 25 | −0.14 (−1.66, 1.39) | 2.64 (−0.61, 4.68) | 0.03 |
25–29.9 | 1.90 (−1.92, 5.72) | −2.61 (−6.43, 1.21) | 0.10 |
> 30 | −0.79 (−3.81, 2.24) | −2.10 (−4.90, 0.69) | 0.53 |
ASUI (↑) | |||
< 25 | 0.09 (0.03, 0.14) | 0.14 (0.07, 0.21) | 0.21 |
25–29.9 | 0.04 (−0.02, 0.11) | 0.10 (0.03, 0.16) | 0.25 |
> 30 | −0.008 (−0.06, 0.04) | 0.07 (0.03, 0.12) | 0.02 |
ACT (↑) | |||
< 25 | 3.34 (2.07, 4.61) | 2.93 (1.37, 4.49) | 0.68 |
25–29.9 | 2.38 (0.83, 3.92) | 3.96 (2.41, 5.51) | 0.15 |
> 30 | 1.98 (0.76, 3.19) | 2.14 (1.00, 3.27) | 0.85 |
SNOT22 (↓) | |||
< 25 | −4.93 (−10.12, 0.27) | −13.10 (−19.57, −6.63) | 0.053 |
25–29.9 | −8.12 (−15.19, −1.05) | −13.90 (−21.18, −6.62) | 0.26 |
> 30 | −6.25 (−12.37, −0.14) | −10.08 (−15.69, −4.47) | 0.36 |
Numbers shown are mean and SD
↑ higher score indicative of better control, ↓ lower score indicative of better control
V2 is baseline visit, V5 is end of study visit.