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. Author manuscript; available in PMC: 2018 Aug 5.
Published in final edited form as: Dev Neurosci. 2017 Aug 5;39(6):443–459. doi: 10.1159/000477898

Fig. 1.

Fig. 1

rhIGF-1 attenuated LPS-induced deficits in locomotor and stereotyped behaviors, as determined by the open field test (crossing distance) (A), total rearing events (B), and stereotyped behaviors (C) of rats. LPS treatment resulted in hyperactivity, whereas rhIGF-1 treatment decreased the LPS-induced hyperactivity in the LPS+rhIGF-1 group. The results are expressed as the mean+SEM of twelve animals in each group and analyzed by two-way repeated measures ANOVA for data from tests conducted continuously at different postnatal days, followed by the Student-Newman-Keuls test. *P<0.05 represents significant difference for the LPS+Vehicle group or LPS+IGF-1 group compared with the Saline+Vehicle group. #P<0.05 represents significant difference for the LPS+IGF-1 group compared with the LPS+Vehicle group.