Table 2.
Incidence of lung carcinoma and lung burden in rats exposed to MWNT-7 for 104 weeks
| Concentration(mg/m3) | Lung carcinoma incidence (%) | Lung burden | ||||
|---|---|---|---|---|---|---|
| Amount of MWNT-7 (µg/g of bw) | Number of MWNT-7 (No/lung) | |||||
| Male | Female | Male | Female | Male | Female | |
| Number of MWNT-7: 1µg=9.03×106 (calculated by SEM) Significant difference; *: p≦0.05 ** : p≦0.01 by Fisher Exact test | ||||||
| 0 | 2 | 0 | - | - | - | - |
| 0.02 | 2 | 2 | 0.029±0.008 | 0.034±0.008 | 0.89×109 | 0.07×109 |
| 0.2 | 16* | 0 | 0.434±0.056 | 0.453±0.056 | 1.38×109 | 1.07×109 |
| 2 | 22** | 16** | 4.954±0.420 | 4.712±0.201 | 16.2×109 | 10.8×109 |