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NF-κB inhibition down-regulated CX3CR1 expression, and CX3CR1 blockade down-regulated the pNF-κB level in the dorsal horn. A, B PDTC down-regulated the CX3CR1 level on days 1 and 3 after TSS. C PDTC attenuated TSS-induced CX3CL1 expression on day 1. D–F CX3CR1 antibody inhibited the TSS-induced phosphorylation of NF-κB. *P < 0.05, **P < 0.01.
