Table 1.
Donor |
Recipient |
Outcome |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Donor | Blood product | Viral load (IU/mL), genotype | Infectious dose (IU) | Anti-HEV IgM/IgG | Recipient, sex and age | Anti-HEV IgGa | Primary disease | Immuno-compromised | Follow-up period (days) | Outcome | HEV-PCR | Anti-HEV IgG | |
1 | RBC (314 mL) | <25 GT 3 | <2.50E+02 | Negative | 1 | M, 23 years | Negative | Heart transplantation | Yes | 134 days | No HEV infection | Negative | Negative |
2 | PC 1 (234 mL) | <25 GT 3 | <4.68E+03 | Negative | 2 | M, 76 years | Negative | Heart valve failure, atrial fibrillation | No | 35 days | No HEV infection, died sepsis | Negative | Negative |
PC 2 (243 mL) | <4.86E+03 | 3 | M, 54 years | Left ventricular heart failure | No | 50 days | No HEV infection | Negative | Negative | ||||
3 donation 1 | PC 1 (230 mL) | 27.8 GT 3 | 5.12E+03 | Negative | 4 | F, 26 years | Negative | Hypertrophic cardiomyopathy | No | 16 days | No HEV infectionb | Negative | Negative |
PC 2 (254 mL) | 5.65E+03 | ||||||||||||
Total | 1.08E+04 | ||||||||||||
3 donation 2 | PC 1 (244 mL) | 69.4 GT 3 | 1.35E+04 | Negative | 5 | M, 72 years | Negative | Arrhythmia | No | NA | Died arrhythmia | NA | NA |
PC 2 (244 mL) | 1.35E+04 | ||||||||||||
Total | 2.71E+04 | ||||||||||||
4 | PC 1 (242 mL) | <25 GT 3 | <3.97E+03 | Negative | 6 | F, 79 years | Negative | Leukemia | Yes | NA | Died leukemia | NA | NA |
PC 2 (244 mL) | <4.00E+03 | ||||||||||||
Total | 7.97E+03 |
aAt the date of transfusion.
bPatient no longer available.