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. 2018 Jan 24;60(3):247–254. doi: 10.1007/s00234-017-1971-3

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Two-year change of fractional anisotropy (FA) in the putamen in patients with Parkinson’s disease (PD) and healthy controls (HC). Differences in absolute values of FA (values from 2-year MRI minus values from baseline) in the putamen between patients with PD and HCs were analyzed using ANCOVA A modest significant difference was found between PD and HC (β = − 0.248, P = 0.01). Lines extending vertically indicate standard error of mean. Horizontal lines that intersect the vertical lines are means