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. 2017 Nov 15;43(2):407–419. doi: 10.1007/s11064-017-2435-1

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 6 — RNS60 treatment induces the recruitment of CREB to the MOG gene promoter in primary mouse oligodendrocytes. a Positions of two CREs in the mouse MOG gene promoter are shown. Cells were treated with 10% v/v RNS60 for 2 h in serum free media. Then immunoprecipitated chromatin fragments were amplified by semi-quantitative (b CRE-distal; c CRE-proximal) and quantitative (d CRE-distal; e CRE-proximal) PCR as described under “Materials and Methods”. Results are the mean ± SD of three separate experiments. ^a p < 0.001 vs. control