Fig. 1. Transverse magnetic resonance imaging over time in a dog with brain infarct. Three days after middle cerebral artery occlusion, infarcts in the right thalamus and left caudate nucleus appear hypointense to isointense on T1-weighted (T1W) images (A) and hyperintense on T2-weighted (T2W) (B) and fluid-attenuated inversion recovery (FLAIR) (C) images. At 8 days post-occlusion, the lesions appear hyperintense (arrowheads) on T1W images (D), with increased intensity and clear margination on T2W (E) and FLAIR (F) images. At 35 days, the lesions are hypointense on T1W (G), hyperintense on T2W (H), and exhibit a hypointense center with peripheral hyperintensity on FLAIR images (I).