Fig. 4. Proliferation of Brucella abortus in spleens of tannic acid (TA)-treated mice or PBS-treated mice. Mice were orally given TA or PBS from 3 days prior to infection to 14 days post-infection. At 14 days post-infection, mice were sacrificed, and the spleens homogenized and serially diluted in PBS. The number of colony-forming units (CFUs) was counted to assess bacterial proliferation in each spleen. A statistically significant difference from the control group is indicated by an asterisk (^**p < 0.01).