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. 2018 Jan 12;50(1):e425. doi: 10.1038/emm.2017.233

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Copyright © 2018 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Measurement of immune modulation factors in AMSCs after LPS stimulation and CD200 inhibition. (a) CD200 expression was highly increased after LPS stimulation, as compared with levels in the normal group. CD200 expression was silenced after CD200 siRNA transfection and maintained after LPS stimulation. The expression of immune modulation factors (b) TGF-β, (c) IDO and (d) IL-10 increased after LPS stimulation. The expression of all factors decreased after CD200 inhibition and showed small range of recovery after LPS stimulation. *: vs Normal; ^#: vs LPS; vs CD200 inhibition, P<0.05 for each comparison. Data are expressed as the mean standard error of the mean.

Inline graphic — Measurement of immune modulation factors in AMSCs after LPS stimulation and CD200 inhibition. (a) CD200 expression was highly increased after LPS stimulation, as compared with levels in the normal group. CD200 expression was silenced after CD200 siRNA transfection and maintained after LPS stimulation. The expression of immune modulation factors (b) TGF-β, (c) IDO and (d) IL-10 increased after LPS stimulation. The expression of all factors decreased after CD200 inhibition and showed small range of recovery after LPS stimulation. *: vs Normal; ^#: vs LPS; vs CD200 inhibition, P<0.05 for each comparison. Data are expressed as the mean standard error of the mean.