Table 1. Summary of survival and statistical significance in orthotopic tumor-bearing mice.
Group | Median survival (days) | ISRa (%) | P-value |
|||
---|---|---|---|---|---|---|
Wild type | Wild type+IR | ΔRNF138 | ΔRNF138+IR | |||
Wild type | 31 | 0.040 | 0.016 | <0.0001 | ||
Wild type+IR | 33.5 | 8 | 0.040 | 0.103 | <0.0001 | |
ΔRNF138 | 33 | 6 | 0.016 | 0.103 | <0.0001 | |
ΔRNF138+IR | 42.5 | 35 | <0.0001 | <0.0001 | <0.0001 |
ISR, increasing survival rate.