Table 3.

Echocardiographic Measurements for Cohort 1

	Control	STZ
Heart rate, bpm	326 ± 13	287 ± 26
Anterior wall thickness, mm	0.9 ± 0.05	0.9 ± 0.2
Posterior wall thickness, mm	0.8 ± 0.1	0.8 ± 0.1
LV EDD, mm	3.5 ± 0.2	3.2 ± 0.2
LV ESD, mm	2.8 ± 0.2	2.2 ± 0.2a
LV mass, corrected, mg	70.5 ± 5.7	50.5 ± 5.7a
Fractional shortening, %	21.7 ± 1.1	32.6 ± 2.6b

Echocardiograph measurements were conducted 16 weeks after STZ injection before time of euthanasia in cohort 1. Values are means ± SEM (n = 6).

^aP < 0.05.

^bP < 0.01.