Table 6. Epitope Predictionsa.
protein | location | epitope | score |
---|---|---|---|
CotB1 | 54–73 | KHLKSITKNAKECGSSDCEW | 1.000 |
100–119 | GPEKVEGILQDVSCDFVTLI | 0.548 | |
CotB2 | 5–24 | LCCDQIKCLVGETVKVNLRG | 1.000 |
123–142 | GDEVIYVIKSHIKSVSQVVK | 0.932 | |
46–65 | HGELVYYQLKHVKSLVKKVK | 0.702 | |
InhA | 436–455 | DYEKLNKGIGLATYLDQSVT | 1.000 |
692–711 | AIVGTLNGKPTVESSTRFQI | 0.903 | |
513–532 | FKSLYEIEAEYDFLEVHAVT | 0.846 | |
613–632 | TPQFKLDGFAVSNGTEKKSH | 0.832 | |
643–662 | GSDNALKFARGPVYNAGMVV | 0.766 | |
260–279 | DALKAAVDSGLDLSEFDQFD | 0.744 | |
18–37 | TQSAYAETPANKTATSPVDD | 0.708 | |
555–574 | TNGKWIDKSYDLSQFKGKKV | 0.697 | |
189–208 | LFGNEPFTLDDGSKIETFKQ | 0.671 | |
90–109 | LTKEASDFLKKVKDAKADTK | 0.662 | |
CotX1 | 36–55 | QESKTYQISEESITIVDSAD | 1.000 |
106–125 | QINKQETVIRNSRNVTVTTT | 0.534 | |
BC_0987 | none predicted |
Immunogenic regions with location within their respective protein and score based on the SVMTriP algorithm.22 Epitopes recommended by the algorithm are indicated in bold. These were submitted to BLAST and shown to be Bacillus cereus group specific with one exception in S. pneumoniae (see Results and Discussion).