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. 2018 Feb 5;9:30. doi: 10.1186/s13287-018-0788-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Assessment of cardiac function in DIC mice transplanted with CM-mESCs or placebo. Measures performed before (corresponding to day 0) and after (corresponding to day 42) Dox or saline administration, and after cell or placebo injection (corresponding to days 52 and 77, respectively). a Analysis of body weight (BW), b ejection fraction (EF), c, d end-diastolic volume (EDV) and end-systolic volume (ESV) corrected by BW, and e stroke volume (SV). Two-way ANOVA with Bonferroni post test: *p < 0.05 compared to the control group; #p < 0.05 compared to the Dox + placebo group. Data shown as mean ± standard deviation; n = 18 for the control group, n = 13 for the Dox + placebo group and n = 10 for the Dox + CM-mESC group. Dox doxorubicin, CM-mESC cardiomyocytes derived from mouse embryonic stem cell, days