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. 2018 Feb 5;16:6. doi: 10.1186/s12964-018-0217-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Differences in α-KG content and expression of α-KG-metabolizing enzymes between SMMC-7721 and SMMC-7721DOX. a α-KG content in SMMC-7721 and SMMC-7721/DOX cells. b Blots of OGDH, IDH, MDH1, MDH2, GLUD1, and ATP5 in SMMC-7721 and SMMC-7721/DOX cells. c Expression of OGDH, IDH, MDH1, MDH2, GLUD1, and ATP5 in SMMC-7721 and SMMC-7721/DOX cells. Significance: *p < 0.05, **p < 0.01 vs. Control