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. 2018 Feb 5;16:6. doi: 10.1186/s12964-018-0217-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Influence of Mal on the energy metabolism mode. a OCR in a mitochondrial stress test. b Effects of Mal on OCR in a mitochondrial stress test. c ECAR of the culture media in a glycolysis stress test. d Effects of Mal on ECAR in a glycolysis stress test. e Cell respiration (OCR) against glycolysis (ECAR) in SMMC-7721 and SMMC-7721/DOX cells. Significance: *p < 0.05, **p < 0.01 vs. SMMC-7721 or SMMC-7721/DOX