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. 2018 Feb 5;19:39. doi: 10.1186/s12891-018-1955-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Comparison of cytokine profiles in serum in control, hip OA and knee OA cohorts. The serum concentrations of cytokines that were found to be significantly differently between the cohorts examined (a). The significantly different cytokines in each cohort are present in more detail in (b) after Bonferroni correction (p < 0.0012) (* = Significantly different in both serum and synovial fluid). Scatter plot of first 3 components of PCA of cytokine profiles of 3 cohorts demonstrates that the serum cytokine profiles are capable of discriminating the 3 different cohorts (c)