Table 5.
Haplotypes frequencies estimations in the population and association with severe malaria (SM)
| Haplotypes | Frequencies | Case vs. controls (Fisher exact test) | ||
|---|---|---|---|---|
| Global | Case (SM) | Controls (UM + CTR) | ||
| H1 | ||||
| CCA | 0.2 | 0.2 | 0.2 | p = 0.19 |
| H2 | ||||
| GGT OR (95% CI) |
0.17 | 0.24 | 0.14 |
p = 0.03 4.1 (2.1–14.9) |
| H3 | ||||
| GGA | 0.08 | 0.12 | 0.07 | p = 0.11 |
Haplotypes analysis using Thesias program, and description of the association between cases SM (cases) vs. Control group (UM + CTR) using fisher exact test. Haplotype 2 was significantly associated with susceptibility to SM. SM Severe malaria, UM Uncomplicated malaria, CTR Control group. The significant p value of the haplotype H2 is in bold; OR 95% CI values were emphisized in italic format