Table 10.

(A and B) Hematological parameters of the rats in acute and sub-acute oral toxicity tests

A	Acute oral toxicity
Hematological Parameters	Sex	Control	DC 300 mg/kg	DC2000 mg/kg		P value
HGB (g/L)	F (n = 3)	153.00 ± 10.00	145.50 ± 9.50	149.33 ± 17.95		0.789
WBC (10^9/L)	F (n = 3)	6.83 ± 0.23	7.77 ± 0.38	8.05 ± 0.75		0.057
Neutrophil (10^9/L)	F (n = 3)	0.55 ± 0.13	0.56 ± 0.07	0.58 ± 0.14		0.961
Lymphocyte (10^9/L)	F (n = 3)	6.39 ± 0.87	6.72 ± 1.15	7.29 ± 0.52		0.498
Monocyte (10^9/L)	F (n = 3)	0.14 ± 0.03	0.15 ± 0.02	0.18 ± 0.3		0.228
Eosinophil (10^9/L)	F (n = 3)	0.08 ± 0.02	0.10 ± 0.02	0.11 ± 0.02		0.125
Basophil (10^9/L)	F (n = 3)	0.02 ± 0.01	0.03 ± 0.02	0.03 ± 0.02		0.531
B	Sub-acute oral toxicity
Hematological Parameters	Sex	Control	DC 500 mg/kg	DC1000 mg/kg	DC1500 mg/kg	P value
HGB (g/L)	M (n = 5)	149.40 ± 6.47	148.80 ± 5.40	150.40 ± 12.72	156.80 ± 12.91	0.575
	F (n = 5)	156.40 ± 5.81	148.80 ± 7.82	150.60 ± 3.85	153.40 ± 5.81	0.243
WBC (10^9/L)	M (n = 5)	9.22 ± 1.03	9.30 ± 2.45	9.46 ± 1.33	9.56 ± 3.67	0.996
	F (n = 5)	6.86 ± 0.59	7.40 ± 1.15	7.38 ± 0.93	7.82 ± 0.81	0.431
Neutrophil (10^9/L)	M (n = 5)	0.98 ± 0.12	1.01 ± 0.16	1.03 ± 0.18	1.14 ± 0.30	0.626
	F (n = 5)	0.81 ± 0.21	0.77 ± 0.11	0.87 ± 0.17	0.89 ± 0.14	0.646
Lymphocyte (10^9/L)	M (n = 5)	9.66 ± 2.12	9.64 ± 1.67	10.39 ± 1.99	10.77 ± 2.08	0.753
	F (n = 5)	8.22 ± 1.07	8.44 ± 1.22	8.67 ± 1.00	9.20 ± 1.14	0.564
Monocyte (10^9/L)	M (n = 5)	0.16 ± 0.02	0.15 ± 0.02	0.17 ± 0.04	0.19 ± 0.04	0.411
	F (n = 5)	0.17 ± 0.03	0.16 ± 0.03	0.18 ± 0.02	0.18 ± 0.03	0.623
Eosinophil (10^9/L)	M (n = 5)	0.08 ± 0.02	0.09 ± 0.02	0.10 ± 0.02	0.10 ± 0.03	0.388
	F (n = 5)	0.08 ± 0.01	0.09 ± 0.02	0.07 ± 0.03	0.10 ± 0.02	0.215
Basophil (10^9/L)	M (n = 5)	0.06 ± 0.2	0.04 ± 0.03	0.04 ± 0.03	0.04 ± 0.03	0.537
	F (n = 5)	0.02 ± 0.02	0.03 ± 0.02	0.03 ± 0.02	0.04 ± 0.02	0.397

Values expressed as a mean ± standard deviation. Sex (male, M and female, F)

*p-value less than 0.05, (p < 0.05) significant value