Table 12.
Biochemical parameters of the rats in acute oral toxicity test
| Biochemical parameters | Sex | Groups | P value | ||
|---|---|---|---|---|---|
| Control | DC 300 mg/kg | DC 2000 mg/kg | |||
| Urea (mmol/L) | F | 3.80 ± 0.53 | 4.00 ± 0.62 | 4.13 ± 0.29 | 0.727 |
| Creatinine (umol/L) | F | 32.67 ± 1.53 | 32.00 ± 4.58 | 31.67 ± 1.53 | 0.920 |
| Albumin (g/L) | F | 40.67 ± 4.04 | 37.67 ± 3.51 | 36.67 ± 1.53 | 0.350 |
| Globulin (g/L) | F | 24.00 ± 1.00 | 22.33 ± 2.08 | 20.00 ± 2.65 | 0.128 |
| Total bilirubin (umol/L) | F | 2.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | – |
| Conjugate bilirubin (umol/L) | F | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | – |
| ALP (U/L) | F | 166.33 ± 4.73 | 164.67 ± 6.03 | 177.33 ± 7.02 | 0.081 |
| ALT (U/L) | F | 24.67 ± 1.53 | 25.67 ± 1.15 | 26.67 ± 1.53 | 0.296 |
| AST (U/L) | F | 96.00 ± 9.17 | 99.67 ± 7.57 | 107.33 ± 3.06 | 0.216 |
Values expressed as a mean ± standard deviation, n = 3
*p-value less than 0.05, (p < 0.05) significant value