Table 3.

(A and B) Relative organs weight (g%) of rats in acute and sub-acute oral toxicity tests

A		Acute oral toxicity
	Sex	Control	DC 300 mg/kg	DC 2000 mg/kg		P value
Heart	F (n = 3)	0.37 ± 0.02	0.35 ± 0.01	0.35 ± 0.03		0.422
Liver	F (n = 3)	2.58 ± 0.14	2.60 ± 0.12	2.50 ± 0.13		0.601
Kidney	F (n = 3)	0.70 ± 0.02	0.67 ± 0.03	0.68 ± 0.02		0.484
Spleen	F (n = 3)	0.18 ± 0.02	0.18 ± 0.02	0.18 ± 0.01		0.952
Lung	F (n = 3)	0.49 ± 0.01	0.48 ± 0.02	0.48 ± 0.02		0.874
B		Sub-acute oral toxicity
	Sex	Control	DC 500 mg/kg	DC 1000 mg/kg	DC 1500 mg/kg	P value
Heart	M (n = 5)	0.36 ± 0.02	0.35 ± 0.02	0.34 ± 0.02	0.34 ± 0.03	0.757
	F (n = 5)	0.37 ± 0.02	0.37 ± 0.03	0.37 ± 0.02	0.38 ± 0.02	0.938
Liver	M (n = 5)	2.92 ± 0.15	2.81 ± 0.10	2.87 ± 0.17	2.92 ± 0.14	0.593
	F (n = 5)	2.45 ± 0.09	2.38 ± 0.07	2.35 ± 0.05	2.43 ± 0.07	0.114
Kidney	M (n = 5)	0.75 ± 0.02	0.75 ± 0.03	0.76 ± 0.02	0.76 ± 0.03	0.930
	F (n = 5)	0.69 ± 0.03	0.70 ± 0.02	0.70 ± 0.05	0.72 ± 0.04	0.639
Spleen	M (n = 5)	0.19 ± 0.02	0.19 ± 0.02	0.18 ± 0.03	0.19 ± 0.02	0.937
	F (n = 5)	0.18 ± 0.02	0.18 ± 0.02	0.18 ± 0.02	0.19 ± 0.02	0.835
Lung	M (n = 5)	0.40 ± 0.02	0.40 ± 0.02	0.39 ± 0.02	0.42 ± 0.01	0.241
	F (n = 5)	0.49 ± 0.02	0.48 ± 0.02	0.49 ± 0.01	0.50 ± 0.02	0.536

Values expressed as a mean ± standard deviation. Sex (male, M and female, F)

*p-value less than 0.05, (p < 0.05) significant value