Table 5.
A | Acute oral toxicity | |||||
Sex | Control | DC 300 mg/kg | DC 2000 mg/kg | P value | ||
Week 1 | F (n = 3) | 64.68 ± 2.80 | 63.43 ± 2.87 | 59.14 ± 14.67 | 0.089 | |
Week 2 | F (n = 3) | 66.16 ± 2.89 | 67.05 ± 5.14 | 63.74 ± 2.15 | 0.236 | |
B | Sub-acute oral toxicity | |||||
Sex | Control | DC 500 mg/kg | DC 1000 mg/kg | DC 1500 mg/kg | P value | |
Week 1 | M (n = 5) | 81.75 ± 1.21 | 81.15 ± 2.17 | 80.99 ± 2.55 | 79.26 ± 2.42 | 0.189 |
F (n = 5) | 74.87 ± 2.59 | 72.99 ± 1.63 | 72.47 ± 2.28 | 71.55 ± 2.80 | 0.089 | |
Week 2 | M (n = 5) | 84.52 ± 1.13 | 83.93 ± 0.93 | 83.80 ± 1.77 | 82.59 ± 1.11 | 0.061 |
F (n = 5) | 78.69 ± 3.26 | 77.56 ± 3.21 | 75.99 ± 3.58 | 74.66 ± 4.64 | 0.220 | |
Week 3 | M (n = 5) | 88.05 ± 2.54 | 87.92 ± 2.07 | 86.10 ± 1.94 | 85.19 ± 2.58 | 0.075 |
F (n = 5) | 86.55 ± 3.64 | 86.15 ± 3.11 | 85.17 ± 3.75 | 83.21 ± 3.68 | 0.320 | |
Week 4 | M (n = 5) | 91.84 ± 1.60 | 91.08 ± 0.79 | 90.30 ± 1.26 | 90.23 ± 1.11 | 0.069 |
F (n = 5) | 88.69 ± 3.66 | 87.35 ± 3.26 | 87.75 ± 3.32 | 87.04 ± 2.77 | 0.798 |
Values expressed as a mean ± standard deviation. Sex (male, M and female, F)
*p-value less than 0.05, (p < 0.05) significant value