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. 2018 Feb 5;18:50. doi: 10.1186/s12906-018-2110-3

Table 5.

(A and B) Food consumption (g) of rats in acute and sub-acute oral toxicity tests

A Acute oral toxicity
Sex Control DC 300 mg/kg DC 2000 mg/kg P value
 Week 1 F (n = 3) 64.68 ± 2.80 63.43 ± 2.87 59.14 ± 14.67 0.089
 Week 2 F (n = 3) 66.16 ± 2.89 67.05 ± 5.14 63.74 ± 2.15 0.236
B Sub-acute oral toxicity
Sex Control DC 500 mg/kg DC 1000 mg/kg DC 1500 mg/kg P value
 Week 1 M (n = 5) 81.75 ± 1.21 81.15 ± 2.17 80.99 ± 2.55 79.26 ± 2.42 0.189
F (n = 5) 74.87 ± 2.59 72.99 ± 1.63 72.47 ± 2.28 71.55 ± 2.80 0.089
 Week 2 M (n = 5) 84.52 ± 1.13 83.93 ± 0.93 83.80 ± 1.77 82.59 ± 1.11 0.061
F (n = 5) 78.69 ± 3.26 77.56 ± 3.21 75.99 ± 3.58 74.66 ± 4.64 0.220
 Week 3 M (n = 5) 88.05 ± 2.54 87.92 ± 2.07 86.10 ± 1.94 85.19 ± 2.58 0.075
F (n = 5) 86.55 ± 3.64 86.15 ± 3.11 85.17 ± 3.75 83.21 ± 3.68 0.320
 Week 4 M (n = 5) 91.84 ± 1.60 91.08 ± 0.79 90.30 ± 1.26 90.23 ± 1.11 0.069
F (n = 5) 88.69 ± 3.66 87.35 ± 3.26 87.75 ± 3.32 87.04 ± 2.77 0.798

Values expressed as a mean ± standard deviation. Sex (male, M and female, F)

*p-value less than 0.05, (p < 0.05) significant value