Table 3.
Immunophenotypic characterization of mesenchymal stromal cells
| CV-MSC (%) | BM-MSC (%) | UC-MSC (%) | AT-MSC (%) | |
|---|---|---|---|---|
| CD44 | 94.9 | 97.4 | 93.3 | 93.9 |
| CD73 | 83.4 | 74.2 | 82.2 | 96.4 |
| CD105 | 76.3 | 95.7 | 66.3 | 94.0 |
| CD90 | 40.8 | 81.0 | 85.8 | 96.9 |
| HLA-ABC | 51.1 | 81.0 | 81.9 | 81.0 |
| CD34 | 1.4 | 0.5 | 1.5 | 2.5 |
| CD45 | 0.3 | 0.2 | 3.4 | 0.1 |
| α-SMA | 92.5 | 18.4 | 9.8 | 27.5 |
| SM22α | 50.5 | 48.4 | – | 45.7 |
| CD49a | 71.2 | 91.2 | 52.7 | – |
| CD146 | 64.3 | 18.8 | 52.1 | 63.1 |
| CD166 | 63.2 | 73.1 | 53.6 | 85.2 |
| CD106 | 62.5 | 68.0 | 61.2 | 4.3 |
| Stro-1 | 44.0 | 9.8 | 2.6 | 2.3 |
| vWF | 18.4 | 12.5 | 6.3 | 6.2 |
| CD14 | 14.1 | 2.0 | 1.1 | 0.1 |
| CD19 | 2.4 | 0.5 | 0.3 | – |
| CD56 | 4.5 | 3.5 | 2.8 | 2.0 |
| HLA-DR | 0.3 | 0.2 | 0.2 | 0.2 |
| CD40 | 2.6 | 2.8 | 1.6 | – |
| CD80 | 0.6 | 0.4 | 0.7 | – |
| CD83 | 2.0 | 3.0 | 2.6 | – |
| CD86 | 0.9 | 0.3 | 0.2 | – |
| CD275 | 1.1 | 0.2 | 0.1 | – |
| CD16 | – | – | – | 5.6 |
| CD31 | – | – | – | 0.1 |
| CD49d | – | – | – | 42.2 |
| CD13 | – | – | – | 75.2 |
| CD29 | – | – | – | 98.2 |
Results expressed as mean percentage of marker expression. CV-MSC of passages 3–5 (n = 5), BM-MSC of passages 2–3 (n = 4), UC-MSC of passage 2 (n = 4), AT-MSC of passages 2–4 (n = 8)
AT adipose tissue, BM bone marrow, CV chorionic villi, MSC mesenchymal stromal cells, UC umbilical cord