Table 1.

Anthropometry of mice after 9 weeks of HFD and AuNP treatments

	Chow-C	HFD-C	HFD-LAu	HFD-HAu
Body weight initial (g)	20.2 ± 0.3	20.2 ± 0.3	20.3 ± 0.2	20.2 ± 0.3
Body weight final (g)	27.7 ± 0.3	37.5 ± 1.2*	34.5 ± 0.8*†	35.8 ± 0.6*
Energy intake (kJ/day)	44.9 ± 0.6	48.4 ± 1.4	50.5 ± 1.4*	52.3 ± 1.4*†
Heart (g)	0.135 ± 0.002	0.145 ± 0.004	0.138 ± 0.004	0.141 ± 0.004
Heart (%)	0.49 ± 0.01	0.40 ± 0.01*	0.39 ± 0.02*	0.40 ± 0.01*
Kidney (g)	0.165 ± 0.004	0.192 ± 0.005*	0.179 ± 0.004*	0.188 ± 0.005*
Kidney (%)	0.59 ± 0.01	0.51 ± 0.02*	0.49 ± 0.02*	0.53 ± 0.02*
Liver (g)	1.34 ± 0.03	1.86 ± 0.12*	1.49 ± 0.03*†	1.54 ± 0.04*†
Liver (%)	4.86 ± 0.08	5.03 ± 0.12	4.27 ± 0.07*†	4.30 ± 0.10*†
Retroperitoneal fat (g)	0.097 ± 0.006	0.761 ± 0.054*	0.652 ± 0.044*	0.616 ± 0.048*†
Retroperitoneal fat (%)	0.35 ± 0.02	2.01 ± 0.10*	1.86 ± 0.11*	1.77 ± 0.09*†
Mesenteric fat (g)	0.372 ± 0.018	0.939 ± 0.075*	0.741 ± 0.060*†	0.691 ± 0.029*†
Mesenteric fat (%)	1.35 ± 0.06	2.46 ± 0.14*	2.07 ± 0.28*†	1.97 ± 0.07*†
Epididymal fat (g)	0.405 ± 0.013	2.029 ± 0.19*	1.77 ± 0.12*	1.80 ± 0.09*
Epididymal fat (%)	1.43 ± 0.06	5.38 ± 0.35*	5.07 ± 0.14*	4.98 ± 0.19*
Plasma insulin (ng/ml)	1.05 ± 0.12	1.09 ± 0.12	1.44 ± 0.21*†	1.11 ± 0.05
Plasma NEFA (nm)	2.54 ± 0.16	4.51 ± 0.54*	2.9 ± 0.24†	3.14 ± 0.35†
Plasma cholesterol (mm)	6.24 ± 0.31	11.14 ± 0.36*	9.40 ± 0.29*†	9.46 ± 0.41*†
Plasma triglyceride (mm)	0.75 ± 0.05	0.86 ± 0.05	0.67 ± 0.04†	0.69 ± 0.05†
Liver triglyceride (mm/mg)	0.023 ± 0.005	0.124 ± 0.019*	0.139 ± 0.007*	0.145 ± 0.010*
Plasma ALT (U/L)	17.3 ± 6.2	55.9 ± 13*	25.5 ± 6.9†	26.3 ± 2.4†
Plasma AST (U/L)	6.33 ± 2.16	31.4 ± 7.1*	16.9 ± 3.9†	12.1 ± 2.2†

Data are expressed in mean ± S.E.M. Data were analyzed using one-way ANOVA, followed by post hoc Bonferroni tests

n = 20/group for anthropometry markers; n = 8/group for plasma insulin, NEFA, cholesterol, triglyceride, and liver triglyceride concentrations; n = 6/group for plasma ALT and AST concentration

* P < 0.05 vs. Chow-C; ^† P < 0.05 vs. HFD-C