Table 1.
General physicochemical properties of estrogens used in this study.
| Parameters | E3 | BPA | 17β-E2 | EE2 | Reference |
|---|---|---|---|---|---|
| MW (g/mol) | 288.4 | 228.3 | 272.0 | 296.4 | [29,30] |
| VP (Pa) | 6.7 × 10−5 | 4.0 × 10−8 | 2.3 × 10−3 | 4.5 × 10−11 | [29,30,31,32] |
| pKa | 10.4 | 10.7 | 10.5 | 11.3 | [30,33] |
| logKow | 2.60 | 3.30 | 4.15 | 3.64 | [29] |
| Sw (mg/L) | 13 | 12 | 13 | 4.8 | [29,30] |
MW = molecular weight. VP = vapor pressure. Ka = acid ionization constant. Kow = octanol–water partition coefficient. Sw = solubility in water. E3 = estriol. 17β-E2 = 17β-estradiol. BPA = bisphenol A. EE2 = 17α-ethinyloestradiol.