Exposure to ambient air particles provokes mood-related behaviors disorder. (a–c) Unfiltered mice spend less time in the center area of the open field arena in the open field test (OFT) (p < 0.05, t18 = 2.161), the open arm of the elevated plus maze test (EPM) (p < 0.001, t18 = 6.333) and the light side of the light-dark box test (L/DBT) (p < 0.001, t18 = 7.776). (d) Unfiltered mice displayed significantly more immobility than filtered mice in forced swim test (FST) (p < 0.01, t18 = 3.688). (e) The time in the interaction area of unfiltered mice was less than that of filtered mice in social interaction test (SIT) (p < 0.05, t18 = 2.583). * p < 0.05; *** p < 0.001.