Table 5.

Accuracy of the GEP test and sentinel lymph node status

	GEP Class	SLN status
	% (95% CI)	% (95% CI)
RFS
Sensitivity	70% (62–78%)	66% (57–74%)
Specificity	71% (67–76%)	65% (58–71%)
PPV	48% (41–55%)	52% (44–60%)
NPV	87% (82–90%)	76% (69–82%)
DMFS
Sensitivity	75% (66–83%)	67% (57–76%)
Specificity	69% (65–74%)	62% (55–68%)
PPV	40% (33–47%)	42% (34–50%)
NPV	91% (87–94%)	82% (76–88%)
MSS
Sensitivity	85% (72–94%)	79% (63–90%)
Specificity	64% (60–69%)	58% (52–64%)
PPV	19% (14–25%)	21% (15–28%)
NPV	98% (95–99%)	95% (91–98%)

CI confidence interval, DMFS distant metastasis-free survival, GEP gene expression profile, MSS melanoma-specific survival, NPV negative predictive value, PPV positive predictive value, RFS recurrence-free survival, SLN sentinel lymph node