Table 1.

Differences of body weight of Plasmodium-infected Swiss mice before (D0) and after infection and administration of the extracts of T. macroptera roots (TMR) and leaves (TML) at 4, 7 and 9 days post-infection (D4, D7, D9)

Infection group	Treatment group	n	D4–D0 ± SEM	n	D7–D0 ± SEM
P. chabaudi chabaudi	Vehicle	6	0.54 ± 0.22	6	0.46 ± 0.51
	CQ	6	− 0.23 ± 0.43	6	− 1.03 ± 0.48*
	TML	6	− 0.57 ± 0.43*	6	0.17 ± 0.43
	TMR	6	0.22 ± 0.19	6	0.74 ± 0.36§

Infection group	Treatment group	n	D4–D0	n	D9–D0
P. berghei ANKA	Vehicle	6	0.67 ± 0.33	0	–
	CQ	6	− 0.01 ± 0.40	5	− 0.31 ± 0.89
	TML	6	0.12 ± 0.42	4	− 2.16 ± 1.17
	TMR	6	0.11 ± 0.44	3	− 4.4 ± 1.31§

Chloroquine (CQ) was used as positive control

SEM standard error of mean

* Comparison of mice treated with CQ or extracts to those that received vehicle. * P < 0.05

^§Comparison of mice treated with extracts to those that received CQ. ^§P < 0.05