Table 5.
Comparison of clinical and infection parameters between catheter subtypes
| Plain (n=161) |
Antibiotic-impregnated (n=188) | Silver-bearing (n=146) |
p Value | ||||
| No. | % | No. | % | No. | % | ||
| 30-day infection | |||||||
| No | 149 | 92.6 | 174 | 92.6 | 126 | 86.3 | 0.09 |
| Yes | 12 | 7.5 | 14 | 7.4 | 20 | 13.7 | |
| Time to infection (median) | |||||||
| 8 (1–29) | – | 11 (2–29) | – | 7 (1–39) | – | 0.19 | |
| Length of antibiotic therapy for ERI (median) | |||||||
| 7.5 (1–28) | – | 14 (1–87) | – | 10 (1–37) | – | 0.23 | |
| Cultured microorganisms | |||||||
| Coagulase-negative staphylococcus (p) | 4 | 36.3 | 2 | 25.0 | 4 | 40.0 | – |
| Staphylococcus aureus (p) | 3 | 27.3 | 2 | 25.0 | 1 | 10.0 | – |
| Enterococcus spp. (p) | 1 | 9.1 | 2 | 25.0 | – | – | – |
| Enterobacter spp. (n) | – | – | 1 | 12.5 | 1 | 10.0 | – |
| Klebsiella pneumoniae (n) | 1 | 9.1 | – | – | 1 | 10.0 | – |
| Morganella morganii (n) | – | – | – | – | 1 | 10.0 | – |
| Escherichia coli (n) | 1 | 9.1 | – | – | – | – | – |
| Klebsiella (n) | 1 | 9.1 | – | – | – | – | – |
| Pseudomonas aeruginosa (n) | – | – | – | – | 1 | 10.0 | – |
| Corynebacterium (p) | – | – | 1 | 12.5 | – | – | – |
| Streptococcus spp. (p) | – | – | – | – | 1 | 10.0 | – |
| 30-day mortality* | |||||||
| No | 100 | 70.4 | 145 | 81.0 | 93 | 71.0 | 0.05 |
| Yes | 42 | 29.6 | 34 | 19.0 | 38 | 29.0 | |
| 30-day mRS* | |||||||
| Good (mRS 0–2) | 50 | 35.2 | 79 | 44.1 | 35 | 26.7 | 0.01 |
| Poor (mRS 3–5) | 50 | 35.2 | 66 | 36.9 | 58 | 44.3 | |
| Death | 42 | 29.6 | 34 | 19.0 | 38 | 29.0 | |
*30-day mortality and 30-day mRS based on 452 non-duplicate patients; (p)=gram stain positive; (n)=gram stain negative.
ERI, external ventricular drain-related infection; mRS, modified Rankin Score.