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Effects of FAC on the levels of sAPPβ and Aβ1-40 (Aβ) in the media of primary cortical neurons. (A) A representative immunoblot and densitometric analysis of secreted sAPPβ. (B) Conditioned media from neurons pretreated for 2 h without or with iron chelator DFO or antioxidant NAC and another 24 h incubation without or with FAC were gathered for ELISA detection of Aβ. ns=non-significant, ##P<0.01.
