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. 2018 Feb 6;13(2):e0190923. doi: 10.1371/journal.pone.0190923

Table 3. Factors affecting renal outcomes in patients with diabetic nephropathy (training set).

Hazard ratio 95% CI p-value
Age per year 0.98 0.96 0.99 0.01
Gender (male) 0.84 0.56 1.24 0.38
eGFR (per 10ml/min/1.73m2) 0.83 0.75 0.92 0.00
Mean Blood pressure (mmHg) 1.02 1.00 1.03 0.03
Body Mass Index (kg/m2) 0.98 0.94 1.03 0.49
Hemoglobin A1c (%) 0.92 0.83 1.02 0.13
Diabetic retinopathy 0.80 0.52 1.23 0.32
Albuminuria normo
micro 1.96 0.48 8.06 0.35
macro 5.43 1.57 18.80 0.01
nephrotic 11.02 2.94 41.35 <0.001
Urinary RBC 1.79 1.09 2.95 0.02
J-score ≦5
6–10 10.98 2.32 51.90 0.002
11–15 17.82 3.88 81.91 <0.001
16–19 36.47 7.61 174.79 <0.001

Abbreviation: CI, confidence interval; J-score: Japanese diabetic pathological score, eGFR: estimated glomerular filtration rate; RBC, red blood cell; Renal outcomes, 50% reduction of eGFR or dialysis initiation.