Table 3. Factors affecting renal outcomes in patients with diabetic nephropathy (training set).
Hazard ratio | 95% CI | p-value | |||
---|---|---|---|---|---|
Age | per year | 0.98 | 0.96 | 0.99 | 0.01 |
Gender | (male) | 0.84 | 0.56 | 1.24 | 0.38 |
eGFR (per 10ml/min/1.73m2) | 0.83 | 0.75 | 0.92 | 0.00 | |
Mean Blood pressure | (mmHg) | 1.02 | 1.00 | 1.03 | 0.03 |
Body Mass Index | (kg/m2) | 0.98 | 0.94 | 1.03 | 0.49 |
Hemoglobin A1c | (%) | 0.92 | 0.83 | 1.02 | 0.13 |
Diabetic retinopathy | 0.80 | 0.52 | 1.23 | 0.32 | |
Albuminuria | normo | ||||
micro | 1.96 | 0.48 | 8.06 | 0.35 | |
macro | 5.43 | 1.57 | 18.80 | 0.01 | |
nephrotic | 11.02 | 2.94 | 41.35 | <0.001 | |
Urinary RBC | 1.79 | 1.09 | 2.95 | 0.02 | |
J-score | ≦5 | ||||
6–10 | 10.98 | 2.32 | 51.90 | 0.002 | |
11–15 | 17.82 | 3.88 | 81.91 | <0.001 | |
16–19 | 36.47 | 7.61 | 174.79 | <0.001 |
Abbreviation: CI, confidence interval; J-score: Japanese diabetic pathological score, eGFR: estimated glomerular filtration rate; RBC, red blood cell; Renal outcomes, 50% reduction of eGFR or dialysis initiation.