Table 5. Summary of adjusted outcomes comparing different DES types with CABG using different adjustment methods.
PCI (n) |
CABG (n) |
Multivariable analyses | IPTW analyses | IV analyses | ||||
---|---|---|---|---|---|---|---|---|
30-DAY MORTALITY | ||||||||
PES vs. CABG | 377 | 4388 | HR = 0.55 (0.08,3.94) | p = 0.554 | HR = 0.53 (0.19,1.47) | p = 0.227 | Δ = 0.7 (-2.2,3.6) | p = 0.640 |
SES vs. CABG | 475 | 4388 | HR = 0.88 (0.38,2.04) | p = 0.773 | HR = 1.11 (0.57,2.16) | p = 0.752 | Δ = 2.3 (-3.4,8.0) | p = 0.423 |
EES vs. CABG | 286 | 4388 | HR = 1.15 (0.50,2.64) | p = 0.744 | HR = 1.76 (0.90,3.43) | p = 0.098 | Δ = -2.2 (-8.1,3.4) | p = 0.471 |
ZES vs. CABG | 922 | 4388 | HR = 1.77 (1.18,2.66) | p = 0.006 | HR = 2.75 (1.94,3.90) | p<0.001 | Δ = 1.5 (-3.8,6.9) | p = 0.573 |
1-YEAR MORTALITY | ||||||||
PES vs. CABG | 377 | 4388 | HR = 1.33 (0.54,3.24) | p = 0.536 | HR = 0.79 (0.43,1.46) | p = 0.451 | Δ = 1.6 (-2.4,5.5) | p = 0.436 |
SES vs. CABG | 475 | 4388 | HR = 1.41 (0.85,2.33) | p = 0.185 | HR = 1.67 (1.12,2.50) | p = 0.013 | Δ = 6.3 (-1.6,14.1) | p = 0.116 |
EES vs. CABG | 286 | 4388 | HR = 1.47 (0.85,2.54) | p = 0.175 | HR = 1.75 (1.07,2.88) | p = 0.028 | Δ = 1.1 (-6.8,8.9) | p = 0.792 |
ZES vs. CABG | 922 | 4388 | HR = 1.65 (1.21,2.27) | p = 0.002 | HR = 2.01 (1.52,2.66) | p<0.001 | Δ = 0.2 (-3.4,3.8) | p = 0.887 |
3-YEAR MORTALITY | ||||||||
PES vs. CABG | 377 | 4388 | HR = 1.25 (0.67,2.36) | p = 0.486 | HR = 1.32 (0.93,1.88) | p = 0.128 | Δ = 5.3 (0.1,10.6) | p = 0.048 |
SES vs. CABG | 475 | 4388 | HR = 1.51 (1.05,2.17) | p = 0.026 | HR = 1.77 (1.32,2.36) | p<0.001 | Δ = 10.9 (0.5,21.2) | p = 0.039 |
EES vs. CABG | 286 | 4388 | HR = 1.36 (0.82,2.26) | p = 0.240 | HR = 1.60 (1.00,2.47) | p = 0.053 | Δ = 2.8 (-3.8,9.4) | p = 0.407 |
ZES vs. CABG | 922 | 4388 | HR = 1.77 (1.36,2.31) | p<0.001 | HR = 1.90 (1.49,2.42) | p<0.001 | Δ = 1.6 (-7.2,10.4) | p = 0.717 |
5-YEAR MORTALITY | ||||||||
PES vs. CABG | 377 | 4388 | HR = 1.63 (1.03,2.55) | p = 0.036 | HR = 1.54 (1.17,2.03) | p = 0.002 | Δ = 12.3 (6.2,18.3) | p<0.001 |
SES vs. CABG | 475 | 4388 | HR = 1.54 (1.14,2.09) | p = 0.005 | HR = 1.66 (1.29,2.12) | p<0.001 | Δ = 16.5 (4.8,28.2) | p = 0.006 |
EES vs. CABG | 286 | 4388 | HR = 1.31 (0.79,2.17) | p = 0.298 | HR = 1.59 (1.01,2.49) | p = 0.046 | Δ = -3.9 (-11.3,3.5) | p = 0.777 |
ZES vs. CABG | 922 | 4388 | HR = 1.78 (1.38,2.29) | p<0.001 | HR = 1.87 (1.49,2.36) | p<0.001 | Δ = -1.4 (-11.2,8.4) | p = 0.867 |
All adjusted ratios are referent to PCI. Highlighted boxes indicate comparable outcomes with PCI and CABG.