Fig. 3.

Substances present in urine screen and date urine sample collected (prescribed dose of buprenorphine in mg/day).

The red italicized font indicates the dose reduction to 24 mg/day of buprenorphine. Blue shading indicates period in which patient experienced withdrawal symptoms. *This urine screen indicates an absence of buprenorphine, which suggests medication nonadherence. **These substance use screenings were performed via oral swab, and the absence of buprenorphine in the results does not imply a lack of medication adherence. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)